

Later, Goblin confronts Spider-Man again and is defeated, but tells Spider-Man of bombs planted downtown. Spider-Man defeats the Goblin at the yearly OsCorp Unity Day Festival. Meanwhile, Norman Osborn is fired from OsCorp and takes his own untested super-soldier serum to become the forever-feared Green Goblin.

Spider-Man wins, but the Scorpion escapes. After Spider-Man helps Scorpion defeat the machines, the apparently paranoid and unhinged Scorpion turns on Spidey, and they fight. Peter goes down to the subways to take pictures of his battle site with Shocker, when he runs into Scorpion. Spider-shaped robots pursue a desperate Scorpion through the sewers. Osborn's scientists tell him that now two individuals with arachnid DNA are at large in Manhattan, and Osborn orders the capture of both.

Spider-Man defeats Vulture atop the Chrysler Building. Spider-Man climbs Vulture's tower, but Vulture escapes. Afterward, Shocker tells Spider-Man about Vulture's lair: an old clocktower on the Lower East Side of town. His battle with Shocker leads him through Grand Central Station, into the sewers and to a subway station, where Spider-Man defeats him in a climactic battle. Meanwhile, the Shocker has just robbed a bank, and is driving away with his thugs as Spidey lands, only to be hit by Vulture. Spider-Man fights these robots and emerges victorious. Anxious to develop his Human Performance Enhancer "Super-Soldier" Serum, the main goals of which are already exhibited by the super-hero, Osborn orders the capture of Spider-Man, deploying hunter-killer robots for this purpose. Meanwhile, Norman Osborn and OsCorp are investigating the appearance of this new hero. Peter then vows to use his powers for good and to fight evil in Manhattan. Peter hunts the killer and manages to defeat him and his entire gang. After competing in a wrestling match as Spider-Man, Peter is devastated when his Uncle Ben is killed by the leader of the Skulls gang Spike. The story begins as Peter Parker develops super-spider powers after being bitten by a genetically altered spider.

Shocker's Vibro-Shock Gauntlets (First appearance).Hunter Killer Robots (Spiders) (First appearance).OsCorps Ultimate Weapon (First appearance).Super Soldier Robots (First appearance).Green Goblin (Mercenary) (First and only known appearance).Kraven the Hunter (Sergei Kravinoff) (First appearance) (Xbox and GBA only).Scorpion (MacDonald Gargan) (First appearance).Vulture (Adrian Toomes) (First and only known appearance).Shocker (Herman Schultz) (First appearance).Green Goblin (Harry Osborn) (First appearance as Green Goblin).
